Software Resources


Click on the link in the Application Name column for more info from the vendor's website.
Application Name Description Availability
SEQUENCE ANALYSIS SOFTWARE
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BIOBASE TRANSFAC v.9.4 Web based gene transcription factor database Citrix
 › Sequence Analysis
  › Biobase
BWA Burrows-Wheeler Aligner is an efficient program that aligns relatively short nucleotide sequences against a long reference sequence such as the human genome. Local installation on informatics LINUX servers
EMBOSS v6.2 with EMBOSS Explorer Web based suite of integrated open source sequence analysis software hosted on COH HPC LINUX clusters Local installation on COH HPC LINUX clusters
Integrative Genomics Viewer v1.4.2 The Integrative Genomics Viewer (IGV) is a high-performance visualization tool for interactive exploration of large, integrated datasets. It supports a wide variety of data types including sequence alignments, microarrays, and genomic annotations. Citrix
 › Sequence Analysis
  › IGV v142
Invitrogen Labshare 3.0 Enable researchers to store and manage Vector NTI dataset in a secure central relational database Citrix
 › Sequence Analysis
  › Labshare
MacVector v.11.1.1 Sequence analysis software for Mac users Local user desktop installation by request
SoftGenetics NextGENe Next Generation Sequencing software BIC Workstation

Citrix
 › Sequence Analysis
  › NextGene
Oligo v.6.71 Oligonucleotides design for PCR, DNA sequencing, site-directed mutagenesis, and various hybridization applications Citrix
 › Sequence Analysis
  › Oligo
Bioconductor R v.2.5 and Rmpi Statistical computing and graphics package
Includes the Bioconductor package which is used for the analysis of DNA microarray data, and genomic data, such as SAGE, sequence, or SNP data
Citrix
 › Sequence Analysis
  › R
Sequencher v.4.8 DNA sequence assembly and analysis software Citrix
 › Sequence Analysis
  › Sequencher
SeqLab SeqLab is the graphical user interface for the Wisconsin Package. Citrix
 › Sequence Analysis
  › SeqLab
SeqWeb v.3.1.2 Sequence analysis suite, including 140 application programs and 11 integrated databases Citrix
 › Sequence Analysis
  › SeqWeb 3
siRNA Site Selector and Duplex-End Energy Difference Calculator: A web-based application that calculates a theoretical difference in thermodynamic stability of the ends of a siRNA duplex, for optimal siRNA
Link
Solar v.4.2.7 Sequential Oligogenic Linkage Analysis software Local installation on informatics LINUX servers
Staden Package v.2.0.0 Sequence handling and analysis software Local installation on informatics LINUX servers
UCSC Genome Browser Updated UCSC Genome Browser with Human (hg19) and Mouse (mm9) database Link
Invitrogen Vector NTI suite v.10 Sequence analysis software Citrix
 › Sequence Analysis
  › Vector NTI
MICROARRAY ANALYSIS SOFTWARE
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BIOBASE TRANSFAC v.9.4 Web based gene transcription factor database Citrix
 › Microarray Analysis
  › Biobase
Gene Cluster 3.0 Cluster 3.0 provides a Graphical User Interface to access to the clustering routines. Citrix
 › Microarray Analysis
  › Cluster
Agilent GeneSpring GX v7.3.1 Performs Agilent expression data analysis suite Citrix
 › Microarray Analysis
  › GeneSpring 73
Agilent GeneSpring GX v11 Performs Agilent expression data analysis suite Citrix
 › Microarray Analysis
  › GeneSpring GX
Integrative Genomics Viewer v1.4.2 The Integrative Genomics Viewer (IGV) is a high-performance visualization tool for interactive exploration of large, integrated datasets. It supports a wide variety of data types including sequence alignments, microarrays, and genomic annotations. Citrix
 › Microarray Analysis
  › IGV v142
ImaGene 7.5 Microarray image analysis tool that automates the time consuming process of measuring and visualizing gene expression data from high-density array images Citrix
 › Microarray Analysis
  › ImaGene 7_5
ImaGene 8 Microarray image analysis tool that automates the time consuming process of measuring and visualizing gene expression data from high-density array images BIC Workstations
Ingenuity Pathways Analysis v7.5 Web application to access biological function literature and pathway database Citrix
 › Microarray Analysis
  › Ingenuity Pathways
MatLab v.R2009a A numerical computing environment and programming language for data visualization and data analysis BIC Workstations

Citrix
 › Microarray Analysis
  › Matlab
OligoArray v.2.0 Genome-scale oligonucleotide design software for microarrays Citrix
 › Microarray Analysis
  › Oligo
Partek Discovery Suite Data analysis and visualization with classical statistics tools to solve complext pattern analysis and recognition problems. BIC Workstations

Citrix
 › Microarray Analysis
  › Partek
Bioconductor R v.2.5 and Rmpi Statistical computing and graphics package
Includes the Bioconductor package which is used for the analysis of DNA microarray data, and genomic data, such as SAGE, sequence, or SNP data
Citrix
 › Microarray Analysis
  › R
Roche NimbleGen SignalMap SignalMap software is a tool that enables you to visualize NimbleGen array data. SignalMap uses GFF files as an input and provides the capability to handle large data sets for graphically-based browsing, rescaling, analysis, and export of graphical files for publication. BIC Workstations

Citrix
 › Microarray Analysis
  › Signal Map 64
MOLECULAR MODELING SOFTWARE
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3D bimolecular structure visualization Academic free software 4 recommended academic downloadable free software, see URL for specific information
AMBER v11 A bimolecular simulation program used for applying molecular mechanics, normal mode analysis, molecular dynamics and free energy calculations to elucidate the structures and energies of molecules Local installation on informatics LINUX server
CHARMM v. c35b3 A program for macromolecular simulations, including energy minimization, molecular dynamics and Monte Carlo simulations Local installation on COH HPC LINUX clusters
Cn3D 4.1 Cn3D simultaneously displays structure, sequence, and alignment, and now has powerful annotation and alignment editing features. Citrix
 › Molecular Modeling
  › Cn3D
Accelrys Discovery Studio Discovery Studio is a life science modeling and simulation suite of applications focused on optimizing the drug discovery process. Discovery Studio makes it easier to examine the properties of large and small molecules, study systems, identify leads and optimize candidates. Citrix
 › Molecular Modeling
  › Discovery Studio
HADDOCK v2.1 A docking software that makes use of biochemical and/or biophysical interaction data such as chemical shift perturbation data resulting from NMR titration experiments or mutagenesis data Local installation on informatics LINUX server
HyperChem v.7.51 A sophisticated molecular modeling environment that combines 3D visualization and animation with quantum chemical calculations, molecular mechanics, and dynamics Citrix
 › Molecular Modeling
  › HyperChem 7_5
MatLab v.R2009a A numerical computing environment and programming language for data visualization and data analysis BIC Workstations

Citrix
 › Molecular Modeling
  › Matlab
NAMD v2.7b2 A parallel molecular dynamics code for large biomolecular systems. Local installation on COH HPC LINUX clusters
PyMOL A molecular visualization system useful for looking at macromolecular 3D structure and creating molecular animations Local installation on linux server (Saturn)

Citrix
 › Molecular Modeling
  › Pymol
Bioconductor R v.2.5 and Rmpi Statistical computing and graphics package
Includes the Bioconductor package which is used for the analysis of DNA microarray data, and genomic data, such as SAGE, sequence, or SNP data
Citrix
 › Molecular Modeling
  › R
Rasmol Molecular visualization software Citrix
 › Molecular Modeling
  › Rasmol
Schrodinger modeling software suite 2010 A molecular modeling suite, including 31 application programs for visualization, homology modeling, docking, and QSAR (network accessible from multiple locations) Local installation on informatics LINUX server
Similarity Pipeline Ligand base Vitural Screening Pipeline Citrix
 › Molecular Modeling
  › Similarity Pipeline
TRIPOS SYBYL-X 1.1 Cheminformatics tool for structure based and ligand based computer assisted molecular modeling package Local installation on informatics LINUX server
Access to LINUX Molecular Modeling workstations Limited SGI O2 and LINUX workstations for access Currently available in the informatics core lab (Bldg.171 Room 1043)


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